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USMLE Step 1: Format, Fee, Blueprint and How to Prepare

USMLE Step 1 is the first US licensing exam for physicians and the basic-science gate for international medical graduates on the ECFMG route. This hub covers the format that began on 14 May 2026, the fee, the pass/fail standard and how to prepare, using USMLE and FSMB pages checked on 25 October 2026.

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Run by USMLE (FSMB + NBME); ECFMG for IMGs. Updated October 2026

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280questions
8 hexam time
5options per question
11blueprint domains
2,000practice questions
How USMLE Step 1 is split by domain
103 sper question on exam day, on average
35questions to answer each hour
11domains in the blueprint
11domains
  • Human development 2%
  • Blood and lymphoreticular/immune systems 11%
  • Behavioral health and nervous systems/special senses 12%
  • Musculoskeletal, skin and subcutaneous tissue 10%
  • Cardiovascular system 9%
  • Respiratory and renal/urinary systems 13%
  • Gastrointestinal system 8%
  • Reproductive and endocrine systems 14%
  • Multisystem processes and disorders 10%
  • Biostatistics, epidemiology and population health 5%
  • Social sciences: ethics, communication and professionalism 6%

Domain shares follow our blueprint for the question bank.

Blueprint by domain

  • Human development2%
  • Blood and lymphoreticular/immune systems11%
  • Behavioral health and nervous systems/special senses12%
  • Musculoskeletal, skin and subcutaneous tissue10%
  • Cardiovascular system9%
  • Respiratory and renal/urinary systems13%
  • Gastrointestinal system8%
  • Reproductive and endocrine systems14%
  • Multisystem processes and disorders10%
  • Biostatistics, epidemiology and population health5%
  • Social sciences: ethics, communication and professionalism6%

USMLE Step 1 is a one-day, pass/fail basic-science exam of up to 280 single-best-answer questions. Since 14 May 2026 it runs as fourteen 30-minute blocks of up to 20 questions inside one 8-hour session at a Prometric test center, with at least 55 minutes of break time. The passing standard is 196 on the former three-digit scale, and the Bulletin says examinees typically need about 60% correct. The application fee is USD 695 (checked 25 October 2026). International medical graduates now register through FSMB after ECFMG accepts their certification application. The most useful tool is the official content outline, which tells you where the questions come from.

What Step 1 is and who sits it

The United States Medical Licensing Examination (USMLE) is a three-step sequence. It is co-sponsored by the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). Step 1 is the first step. The USMLE program describes it as an assessment of whether you understand and can apply the important concepts of the sciences basic to the practice of medicine. In plain terms, it asks whether you can use pathology, physiology, pharmacology, microbiology, biochemistry, anatomy and behavioral science to reason through a patient in front of you.

Two groups sit it. The first is students and graduates of programs accredited by the Liaison Committee on Medical Education (LCME) for MD degrees and by the Commission on Osteopathic College Accreditation (COCA) for DO degrees. Most of them take it after the basic-science phase of their school curriculum. The second is international medical graduates (IMGs), who are students or graduates of non-US schools that meet ECFMG requirements. IMGs usually sit Step 1 as part of the route to ECFMG certification, which is a prerequisite for US residency training. Canadian graduates from 1 July 2025 onward are treated as IMGs under the current rules.

Step 1 has been reported only as pass or fail since 26 January 2022. That changed how people use it. A pass is a pass: there is no score to compete on. It also means the exam cannot be skipped or compensated for by a strong result elsewhere. Step 2 CK and Step 3 are separate exams with their own passing standards. Our guide on Step 1 versus Step 2 CK explains how the two differ in what they test.

MedPass Exams is independent. We are not affiliated with, endorsed by or reviewed by the USMLE program, NBME, FSMB or ECFMG. Everything on this page about the exam comes from the USMLE, FSMB and NBME pages listed at the bottom, checked on 25 October 2026. Where an official page does not say something, we say so instead of guessing.

Eligibility and booking

You must be in an eligible category when you apply and again on the day you test. For MD and DO students that means being enrolled in, or a graduate of, an accredited program. For IMGs it means being a student or graduate of a medical school that ECFMG recognizes, with the required documents accepted. The 2027 Bulletin of Information is the authority, and the eligibility and IMG pathway guide walks through the cases that cause most delays.

A major change took effect in January 2026. Registration for IMGs moved from ECFMG to FSMB on 12 January 2026. US MD and DO students and graduates register through NBME. ECFMG still handles certification, and it must accept your Application for ECFMG Certification before you can apply for your first Step.

  1. Confirm your category. LCME-accredited MD, COCA-accredited DO, or an ECFMG-eligible international medical school. Check that you will still be in this category on your test date.
  2. IMGs: get your ECFMG application accepted. Create a MyIntealth account, complete identity verification and have your Application for ECFMG Certification accepted. US MD and DO students skip this and register with NBME.
  3. Create your registration account. IMGs create an FSMB USMLE account, and the name must match your Intealth record. US students use the NBME site.
  4. Apply for Step 1 and pick an eligibility period. The application fee is USD 695 for the 2026 and 2027 three-month eligibility periods. Pay the exact fee shown at checkout, because other charges exist and are not itemized on the pages we read.
  5. Receive your scheduling permit. You need it to schedule. It carries your eligibility period, so do not let it lapse unnoticed.
  6. Schedule with Prometric. Scheduling usually cannot be made more than six months ahead. Test centers fill, especially for international regions, so book as soon as your permit arrives.

Fees, dates and rules on this page were checked on 25 October 2026. Fees and schedules change. Confirm the current figure on the FSMB fee page before you pay. Our booking and fees guide separates what is confirmed from what we could not verify.

Format and scoring

From 14 May 2026, Step 1 has fourteen blocks. Each block lasts 30 minutes and holds up to 20 questions, which gives a maximum of 280. Before that date the exam used seven 60-minute blocks of up to 40 questions. The total ceiling of 280 did not change, but the rhythm did. You now have about 90 seconds per question inside a block, and the shorter block means a break opportunity comes more often. The 2027 Bulletin describes the exam as one session of about 8 hours with at least 55 minutes of break time and an optional five-minute tutorial. The older figures (45-minute break, 15-minute tutorial) are still quoted on many vendor pages. Do not plan on them.

The main item type is the single-best-answer question. One patient-centered vignette is followed by one question, with four or more lettered options. Official sample items show five or six. Our practice bank uses five. Some items include images, graphs or audio findings. Lab values, a calculator and on-screen note-taking are available during the exam. The USMLE says some items are scored and some are unscored, and both go through the same review. It does not tell you which is which, so treat every question as if it counts.

The scoring story is short. Step 1 is not graded on a curve, so in principle every examinee could pass. The passing standard is 196 on the former three-digit scale, and the Bulletin says examinees typically must answer approximately 60% of questions correctly. That is a typical figure, not a printed cutoff, because the exam is built so that the same standard applies to different question sets. Results are typically available within four weeks of your test date. The USMLE advises allowing at least eight weeks to receive notification that your score report is available. Read what score passes Step 1 for the full explanation, including what a fail report shows.

The official pages we read do not say whether you can go back and change answers within a block, or whether a flagging tool exists. We do not state either as fact. The USMLE interactive testing experience on its website shows the real software. Run it before test day so the interface is familiar.

Blueprint by organ system

The USMLE publishes an integrated content outline. It sets percentage ranges by system, by discipline and by physician task. The systems table is the most useful for planning. The official page gives ranges, not single numbers. Our bank weights sit inside each range and total exactly 100%, and the approximate question counts below are those weights applied to a 280-question exam. Treat the counts as planning estimates, because the USMLE says percentages are subject to change at any time.

SystemOfficial rangeOur weightAbout how many itemsDomain page
Reproductive and endocrine12-16%14%39Reproductive and endocrine
Respiratory and renal/urinary11-15%13%36Respiratory and renal
Behavioral health and nervous systems/special senses10-14%12%34Behavioral and nervous
Blood and lymphoreticular/immune9-13%11%31Blood and immune
Musculoskeletal, skin and subcutaneous tissue8-12%10%28Musculoskeletal and skin
Multisystem processes and disorders8-12%10%28Multisystem
Cardiovascular7-11%9%25Cardiovascular
Gastrointestinal6-10%8%22Gastrointestinal
Social sciences: communication and interpersonal skills6-9%6%17Ethics and communication
Biostatistics and epidemiology/population health4-6%5%14Biostatistics and epidemiology
Human development1-3%2%6Human development

Two things in the outline are easy to miss. First, there is no separate "General Principles" row any longer. Biochemistry, genetics, pharmacology and microbiology are spread through the organ systems, and the multisystem row holds what does not belong to one organ. A question about a drug mechanism sits in the system where the drug works. Second, items are also tagged by discipline and by physician task. About 60-70% of the exam is Medical Knowledge: Applying Foundational Science Concepts, and about 20-25% is Patient Care: Diagnosis. Pathology carries the largest discipline range at 45-55%, with physiology at 30-40%. Those two disciplines are where mechanism-based studying pays off most.

The exam also lists "Nutrition" at 15-20% as a discipline tag. Discipline percentages overlap and total more than 100% because one item can carry several tags, so do not add them up.

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How to prepare: a phased plan

Step 1 rewards three habits: learning mechanisms rather than lists, doing questions daily, and reviewing mistakes in writing. The plan below applies to any timeline. The study plan guide turns it into 8, 12 and 16-week calendars.

  1. Phase 1, diagnosis (week 1). Take one 40-question mixed set, untimed, in a bank you have not used before. The score does not matter. The pattern of errors does. Sort misses into three buckets: did not know, knew but misread, and knew but picked the wrong mechanism.
  2. Phase 2, system-by-system rebuild (about half your time). Take the systems in order of weight and weakness, starting with reproductive/endocrine, respiratory/renal and behavioral/nervous. For each system, read or watch for mechanism, then do 20 to 40 questions in tutor mode and read every explanation, including the ones you got right.
  3. Phase 3, cross-system integration (about a quarter). Switch to mixed, random blocks. This is where multisystem content, pharmacology and microbiology appear in their real mixed form. Move to timed mode and build up to full-length days.
  4. Phase 4, simulation (final 2 to 3 weeks). Run at least two full-length practice days using the 14-block, 30-minute pattern. Practice the break routine as well: eat, drink and reset in the break time you will have on the day. Use the official sample questions and the interactive testing experience for format, not for content prediction.
  5. Phase 5, taper (final 3 days). Review the error log, formulas and tables. Stop new content. Sleep, logistics and test-center travel matter more than another 100 questions.

Dedicated study time is a personal decision. We do not state a universal number of weeks, because the USMLE does not publish one and candidates differ widely in the strength of their basic-science foundation. A graduate years out of school usually needs a longer rebuild than a student fresh from a strong basic-science course.

Common reasons candidates lose marks

The USMLE does not publish causes of failure, and neither do we claim any as proven. What follows is editorial guidance drawn from the structure of the exam. Each one maps to something the outline or the format makes likely.

  • Studying facts without mechanisms. About 60-70% of the exam applies foundational science to a clinical vignette. A memorized list of drug names does not help when the question asks why a drug caused a finding.
  • Ignoring the low-glamour systems. Reproductive/endocrine, respiratory/renal and behavioral/nervous together make up roughly 39% of the bank weights. They are not glamorous, but they are heavy.
  • Reading stems too fast. Many vignettes hide the deciding detail in a vital sign, a lab value with units or a medication in the history. Reading the question stem first, then the vignette, often helps.
  • Neglecting biostatistics and ethics. Together they are roughly 11% of the exam. The rules are finite and learnable, so these are some of the cheapest marks available.
  • Never practicing at full length. Eight hours is a different task from a 40-question set. Stamina, pacing across fourteen short blocks and break management are trainable skills.
  • Using the wrong units and ranges. The exam uses conventional US units for most lab values, with a reference range list available on screen. Practicing only in SI units, or in ranges from another country, creates avoidable misses.
  • Doing questions without reviewing them. Volume without review plateaus. Rewriting each missed concept in one sentence is slower, and it works better.
  • Booking before you are ready, or too late. The scheduling window, your eligibility period and test center availability all constrain you. An eligibility period that expires is an expensive way to find out.

The high-yield topics guide lists the concepts that come back across many systems, and the domain pages give each system its own list of traps.

After the exam

Results are typically available within four weeks of your test date, and the USMLE advises allowing at least eight weeks before you worry. The report states pass or fail. If you do not pass, the report includes performance information by content area, which is useful for planning a retake. The online score report remains available for about 365 days. After that, you need a transcript request.

Attempt limits are strict. You can take the same Step no more than three times in 12 months. The fourth attempt must be at least 12 months after your first attempt and at least six months after your most recent attempt. The 2027 Bulletin also states that an examinee who has attempted a Step four or more times without passing is ineligible for any Step. Older public material quoted a six-attempt lifetime limit, so read the current Bulletin before you plan around either figure. Read what to do if you do not pass for a calm, practical approach.

If you pass, the next exam is Step 2 CK, whose minimum passing score is 218 (from 1 July 2025). Step 3 has a minimum passing score of 200 (from 1 January 2024). IMGs also need ECFMG certification, which has requirements beyond the exams. Check the Intealth and ECFMG sites for what is currently required. A passed Step generally cannot be retaken.

If you are also considering other US licensing exams, such as nursing, see the NCLEX-RN hub. For the wider picture of US exams on MedPass Exams, visit the United States page.

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Using MedPass Exams for Step 1

Our Step 1 bank is original. It follows the official content outline, with questions written as patient vignettes in the same single-best-answer shape, five options, conventional units and American spelling. We do not use recalled or leaked material, and we do not copy the official sample items. The free USMLE sample questions are the right place to see exactly how the real exam looks. Our questions are for practicing the reasoning.

The bank is organized by the same eleven systems as the outline, so you can drill a weak area, or run mixed blocks that mimic the integrated format. Review each block against its explanations and note the concept behind every miss. No bank can guarantee a result, and we do not claim one. Use ours alongside the official materials.

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Where to go next

Sample questions

Original questions in the exam's style. Choose an answer, then check it.

A 41-year-old man with generalized anxiety disorder has a history of benzodiazepine misuse and does not want a medication that causes sedation, dependence, or impairs psychomotor performance. His physician prescribes a drug that must be taken for 1 to 2 weeks before it takes effect. Which of the following is the primary mechanism of this drug?

A 24-year-old man has 8 months of low back pain and stiffness that is worse in the morning and improves with exercise. He now reports a painful, red left eye with photophobia. Lumbar flexion is limited, and radiographs show bilateral sacroiliac joint sclerosis. Which of the following is the most likely cause of his eye symptoms?

A 58-year-old woman undergoes total hip arthroplasty through a direct lateral (transgluteal) approach. Postoperatively, when she stands on her right leg, the left side of her pelvis drops. When walking, she leans her trunk over the right hip. Which of the following nerves was most likely injured?

Exam guides

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One guide per blueprint domain, with worked questions.

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Every plan includes

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  • Timed blocks and full mock exams in the real format
  • Flashcards, study plan and weak-topic tracking
  • Pass predictor (an estimate, not a guarantee)
  • AI tutor for questions you have answered

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Frequently asked questions

How many questions are on USMLE Step 1?

Up to 280 multiple-choice questions, taken in one 8-hour session. Since 14 May 2026 they are split into fourteen 30-minute blocks of up to 20 questions each. Before that date the exam used seven 60-minute blocks of up to 40 questions, so older guides may describe the old layout.

Is USMLE Step 1 pass/fail?

Yes. For exams taken on or after 26 January 2022, Step 1 is reported as pass or fail only, with no three-digit score. The passing standard is 196 on the former three-digit scale, and future reviews will not be reported as three-digit scores.

What percentage do I need to pass Step 1?

The 2027 Bulletin says examinees typically must answer approximately 60% of questions correctly. That is a typical figure, not a fixed printed cutoff. The exam is not curved, so every examinee could pass.

How much does the Step 1 exam cost?

The FSMB lists the Step 1 application fee as USD 695 for the 2026 and 2027 eligibility periods (checked 25 October 2026). Charges for extending an eligibility period, rescheduling or changing test region are separate, so check the fee schedule at checkout.

How do international medical graduates register for Step 1?

Since 12 January 2026, IMGs register through FSMB. You first need your Application for ECFMG Certification accepted, a MyIntealth account and identity verification, then an FSMB USMLE account with a name that matches Intealth. US MD and DO students register through NBME.

How long do Step 1 results take?

Results are typically available within four weeks of your test date. The USMLE advises allowing at least eight weeks to receive notification that your score report is available. The online report stays available for about 365 days.

How many times can I take Step 1?

No more than three attempts of the same Step in 12 months. The fourth attempt must be at least 12 months after the first attempt and at least six months after the most recent one. The current Bulletin also bars examinees who have attempted a Step four or more times without passing, so verify the wording before you plan.

What are the biggest systems on the Step 1 outline?

Reproductive and endocrine (12-16%), respiratory and renal/urinary (11-15%) and behavioral health and nervous systems/special senses (10-14%) have the highest official ranges. Together they make up about 39% of our bank weights.

Can I use a calculator or look up lab values during Step 1?

A built-in calculator and on-screen note-taking are standard, and laboratory reference values are available on screen. Outside materials are not allowed. Check the Bulletin and the USMLE exam-day pages for the current rules at your test center.

Is Step 1 harder now that it is pass/fail?

The USMLE has not said the difficulty changed. What changed is the reporting: a pass is simply a pass. Preparation should aim at clearing the standard with a margin, not at a score target, and at mastering the content outline.

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